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Researchers use tiny drug delivery implant to treat tumors

admin by admin
April 15, 2023
in News


Houston Methodist Research Institute nanomedicine researchers used an implantable nanofluidic drug delivery device smaller than a grain of rice to deliver immunotherapy directly into a pancreatic tumor. [Image courtesy of Houston Methodist]

Researchers at Houston Methodist Research Institute developed a tiny drug delivery device for addressing difficult-to-treat cancers.

The researchers published their work in a paper in Advanced Science. They used an implantable nanofluidic device they invented to deliver CD40 monoclonal antibodies (mAB). The team calls the device a nanofluidic drug-eluting seed (NDES).

With the device  — smaller than a grain of rice — they delivered immunotherapy directly into the tumor at a sustained low dose. This investigation took place in murine (rodent) models.

Researchers observed tumor reduction at a four-fold lower dosage compared to traditional systemic immunotherapy treatment.

Get the full story at our sister site, Drug Delivery Business News.



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